Reinforcement learning-based design of sequential drug treatment targeting the evolving tumour landscape with SequenTx

Nature Machine Intelligence, Published online: 04 March 2026; doi:10.1038/s42256-026-01192-1

Chen et al. introduce SequenTx, a virtual-cell-inspired framework for the rational design of sequential therapy. It offers a computational strategy to navigate therapy-induced tumour evolution by modelling dynamic cellular state transitions.